Canadian Pharmacy Zoloft: General Information and Application
Sertraline hydrochloride (trade name «Zoloft») is an antidepressant of selective serotonin reuptake inhibitor group (SSRI). Canadian Pharmacy Generic Zoloft is primarily issued in cases of major depression at adult outpatients as well as obsessive-compulsive disorders, panic attacks and social anxiety disorders at adults and children. Panic disorders treatment with Zoloft show significant anxiety attacks decrease and quality of life improvement. At obsessive-compulsive disorders, Sertraline is not as effective as cognitive-behavioral therapy. Best results were achieved in a combination of these two methods. Generic Zoloft also relieves late luteal phase dysphoric disorder symptoms and can be used in sub-therapeutic doses or intermittently during treatment. History Zoloft history begins in 1970, when «Pfizer’s» chemist Reinhard Sarges invented a new range of psychoactive compounds based on chlorprothixene and thiothixene neuroleptics structure. Further work on these compounds development led to tametraline, norepinephrine and weaker dopamine reuptake inhibitors creation. Tametraline development was soon frozen due to adverse stimulatory effects observed at animals. A few years later, in 1977, pharmacologist Kenneth Koe, after comparing structural features of various reuptake inhibitors, became interested in tametraline agents. He asked another «Pfizer’s» chemist, Willard Welch, to synthesize some of the previously unknown tametraline derivatives. As a result, Welch created…